| Customization: | Available |
|---|---|
| Certification: | ISO, FDA |
| Assay Method: | HPLC, UV |
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Pure Eucommia Bark Extract Powder is a premium-grade, ultra-concentrated botanical ingredient derived exclusively from the bark of Eucommia ulmoides (commonly known as Du Zhong or "Gutta-Percha Tree"), standardized to an exceptional 98% chlorogenic acid (CAS 327-97-9). Revered in Traditional Chinese Medicine (TCM) for over 2,500 years for its adaptogenic and rejuvenating properties, Eucommia bark is now validated by modern science as a powerhouse of bioactive compounds. Our extract is produced through proprietary multi-stage solvent-free extraction and crystallization technology, achieving pharmaceutical-grade purity while preserving the synergistic phytochemical profile unique to Eucommia. Chlorogenic acid, a potent hydroxycinnamic acid, is the cornerstone of this extract, offering unparalleled antioxidant, anti-inflammatory, and metabolic-modulating benefits. Designed for nutraceutical, cosmeceutical, and functional food applications, this ultra-pure extract meets the stringent demands of high-performance formulations targeting chronic inflammation, oxidative stress, and metabolic syndrome.
Industry-Leading Purity: 98% chlorogenic acid (HPLC-verified), the highest commercially available concentration for precision dosing.
Solvent-Free Production: Utilizes advanced enzymatic hydrolysis and macroporous resin purification to eliminate solvent residues.
Full-Spectrum Synergy: Retains trace amounts of aucubin, geniposidic acid, and lignans for enhanced bioavailability.
Global Compliance: Meets USP, EP, JP, FDA cGMP, and ICH Q7 standards for pharmaceutical ingredients.
Sustainability: Ethically wildcrafted from FSC-certified plantations in China's Qinling Mountains.
Benefits of Chlorogenic Acids
Chlorogenic acids are celebrated for their multifaceted health-promoting effects:
Antioxidant Powerhouse: Neutralizes free radicals, reducing oxidative stress and supporting cellular health.
Metabolic Support: May enhance fat metabolism and energy utilization, aiding healthy weight management.
Blood Sugar Balance: Supports glucose regulation by modulating carbohydrate absorption.
Cardiovascular Wellness: Promotes healthy lipid profiles and vascular function.
Skin Health: Used in cosmetics for its anti-aging and UV-protective properties.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Nutraceuticals:
Metabolic Health: Formulate capsules for glucose regulation (targeting Amp. activation) and weight management.
Cardiovascular Support: Synergize with berberine or olive leaf extract for blood pressure and lipid modulation.
Neuroprotection: Integrate into nootropic blends for mitochondrial support and cognitive longevity.
Pharmaceuticals:
Hypertension Drugs: Active pharmaceutical ingredient (API) for natural antihypertensive formulations.
Diabetes Adjuvants: Enhances insul. sensitivity in combination therapies.
Cosmeceuticals:
Anti-Aging Serums: Stabilized chlorogenic acid inhibits MMP-1 collagenase and UV-induced ROS.
Topical Analgesics: Eucommia's aucubin enhances topical pain relief in transdermal patches.
Functional Foods:
Medical Foods: Fortify bars or shakes for metabolic syndrome management (FDA 21 CFR 101.14 compliant).
| Parameter | Specification |
|---|---|
| Botanical Source | Eucommia ulmoides Bark (Wildcrafted, FSC-Certified) |
| Active Compound | ≥98% Chlorogenic Acid (CAS 327-97-9, HPLC-DAD) |
| Appearance | Fine white to off-white crystalline powder |
| Solubility | Water-soluble (1:50), ethanol-soluble (1:20), pH-stable (2-9) |
| Particle Size | 90% <50 microns (laser diffraction analysis) |
| Heavy Metals | Arsenic <0.1 ppm, Lead <0.2 ppm, Cadmium <0.1 ppm (ICP-MS) |
| Microbial Limits | Total Aerobic Count <100 CFU/g, E. coli Absent, Salmonella Absent (USP <2023>) |
| Residual Solvents | Class 1-3 Solvents Undetectable (GC-FID, per ICH Q3C) |
| Endotoxins | <0.25 EU/mg (LAL test) |
| Certifications | ISO 22000, FSSC 22000, Kosher, Halal, Organic (USDA/EU), Non-GMO Project Verified |
| Storage & Stability | 36 months in vacuum-sealed aluminum pouches at 15-25°C; protect from humidity |
Concentration Flexibility: Adjust chlorogenic acid levels (5%-98%) for niche applications.
Blend Optimization: Combine with other Eucommia actives (e.g., aucubin, geniposidic acid).
Packaging Options:
Retail-Ready: 1 kg/5 kg aluminum foil bags with oxygen absorbers.
Bulk Supply: 25 kg fiber drums with desiccant.
OEM Services: Private labeling, custom blends, and capsule filling.
Hubei Sanxin Pharmaceutical Technology Co., Ltd is a wholly-owned subsidiary of Hubei Sanxin Biotechnology Co., Ltd. Which was established in March 2011, located in Dongcheng Industrial Park, Fangxian, Shiyan City. Our company owns first -class production equipment with the latest technology and testing methods. We specialize in scientific research, development, production, and sales all as one national high-tech enterprise, We also be known for agricultural leading enterprises in Shiyan City. We have GMP planting base with more than 4942 acres, 2 automatic production lines, which can produce more than 800 tons of plant extracts annually. The company has passed FDA certification and Kosher and Halal certification.
Sanxin′s main products are: Polygonum Cuspidatum Extracts (resveratrol, Polydatin, emodin, Physcion and proportional extracts of Polygonum cuspidatum); Pueraria Extracts (pueraria isoflavones, puerarin); Olive Leaf Extract(Oleuropein, Hydroxytyrosol); Tea extract; Baicalin and other standard extracts and proportional extract products. Our products have been widely used in food, health care products, medicines, cosmetics, veterinary medicine, feed additives and many other fields. Now company′s products have been sold to Hunan, Tianjin, Beijing, Shanghai and other places, some of the products have been exported to the United States, Canada, UK, Japan, and other more than 30 countries. Sanxin company′s main spirit is: Be honest be Trustworthy, win-win cooperation! Welcome to our company!
For more information, samples, or to place an order, please contact us. We look forward to partnering with you to deliver high-quality resveratrol powder that meets your needs!
Science-Backed: Chlorogenic acid's efficacy is supported by research on antioxidant capacity and metabolic support.
Sustainable Sourcing: Partnered with eco-conscious farms to ensure ethical raw material procurement.
Global Compliance: Pre-formulated to meet international regulatory requirements for seamless market entry.
Triple Validation: Each batch undergoes identity confirmation (HPTLC), potency testing (HPLC), and contaminant screening (GC-MS/ICP-MS).
Stability Data: Accelerated stability studies confirm >95% potency retention at 40°C/75% RH for 6 months.
Regulatory Dossiers: Available DMF (Type II), CEP, and GRAS dossier for seamless drug and food integration.
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Elevate your product line with the science-backed benefits of the Extract. Contact us today for samples, technical data, or partnership opportunities!
At 98% purity, our extract eliminates unnecessary plant matrix components, enabling precise dosing for clinical applications. Unlike 50% extracts, it bypasses solubility challenges in injectables and allows direct compression in tablet formulations without excipient overload.
Primary Method: HPLC-DAD with reference standard (USP Chlorogenic Acid RS) on a C18 column (LOD 0.01%).
Orthogonal Testing: LC-MS/MS for identity confirmation (m/z 353→191 transition).
Impurity Profiling: Residual solvents by GC-FID, heavy metals via ICP-MS.
Yes. With endotoxin levels <0.25 EU/mg and sterile filtration compatibility (0.22 µm), it meets USP <71> sterility requirements for injectable APIs.
Absolutely. Chlorogenic acid's ORAC value of 20,000 µmol TE/g outperforms BHT (1,200 µmol TE/g) while offering multifunctional benefits (e.g., anti-glycation, Nrf2 activation).
In vitro studies show negligible inhibition of CYP3A4, 2D6, or 2C9 at doses ≤1,000 mg/day, minimizing drug interaction risks (refer to Phytomedicine 2022).
General Health: 100-200 mg/day (antioxidant support).
Therapeutic Use: 300-500 mg/day (hypertension, glucose control).
Safety Threshold: NOAEL established at 2,000 mg/kg/day (90-day rodent study).
Wildcrafting Protocol: Bark harvested sustainably (≤20% per tree) with 5-year rotation cycles.
Carbon Credits: 10% of profits fund reforestation in the Qinling biodiversity hotspot.
Yes. We offer chlorogenic acid in amorphous (enhanced solubility) or crystalline (improved stability) forms, tailored to your formulation's needs.
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