Customization: | Available |
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Certification: | ISO, FDA |
Assay Method: | HPLC |
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Dihydroberberine (DHB, CAS 483-15-8) is a high-purity bioactive alkaloid extracted from Golden Cypress (Berberis aristata), a plant traditionally valued for its medicinal properties. With NSC331264 identification and ≥97% purity, this advanced food additive and nutraceutical ingredient offers superior bioavailability compared to standard berberine, making it ideal for metabolic health formulations. Manufactured in GMP-certified facilities with strict adherence to ISO 9001 standards, our DHB ensures safety, consistency, and compliance with global regulatory requirements.
Enhanced Bioavailability: DHB's hydrogenated structure improves absorption and efficacy.
Natural & Sustainable: Sourced from premium-grade Golden Cypress, ensuring eco-friendly extraction.
Metabolic Support: Promotes healthy blood sugar balance, lipid metabolism, and weight management.
Antioxidant & Anti-inflammatory: Reduces oxidative stress and supports cellular health.
Multi-Industry Applications: Suitable for dietary supplements, functional foods, pharmaceuticals, and cosmeceuticals.
Rigorous Quality Assurance: Tested via HPLC, UV-Vis, and GC-MS to guarantee purity and safety.
Parameter | Specification | Test Method | Remarks |
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CAS Number | 483-15-8 | Chemical Abstracts Service | Unique identifier for chemical compound. |
Molecular Formula | C20H21NO4 | Mass Spectrometry (MS) | Confirmed via high-resolution MS. |
Molecular Weight | 339.39 g/mol | Calculated from formula | - |
Purity | ≥98% | HPLC (High-Performance Liquid Chromatography) | Purity verified by UV detection at 265 nm. |
Appearance | Fine yellow crystalline powder | Visual inspection | Homogeneous, free of visible impurities. |
Solubility | Soluble in ethanol, DMSO; slightly soluble in water | USP <1231> (Solubility test) | Solubility tested at 25°C. |
Melting Point | 145-148°C | DSC (Differential Scanning Calorimetry) | Consistent with reference standards. |
Loss on Drying | ≤0.5% | USP <731> (Loss on Drying) | Determined by drying at 105°C for 2h. |
Residual Solvents | <50 ppm (Ethanol) | GC (Gas Chromatography) | Complies with ICH Q3C guidelines. |
Heavy Metals | <10 ppm (Pb, As, Cd, Hg) | ICP-MS (Inductively Coupled Plasma Mass Spectrometry) | Meets FDA/EFSA safety limits. |
Microbial Limits | Total plate count <1000 CFU/g | USP <61> (Microbiological Testing) | Complies with food-grade standards. |
Storage Conditions | 2-8°C, protected from light and moisture | - | Store in airtight, opaque containers. |
Shelf Life | 24 months | Accelerated stability testing | Valid under recommended storage. |
Certifications | GMP, ISO 9001, Halal/Kosher (upon request) | Third-party audits | Available with supporting documentation. |
Certified Quality: FDA, ISO, and third-party lab certifications ensure premium standards.
Global Compliance: Meets FDA, EFSA, and China GB2760 requirements for food additives.
Technical Expertise: R&D support for formulation optimization and regulatory documentation.
Sustainable Sourcing: Ethically harvested Golden Cypress with traceable supply chains.
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1. What is dihydroberberine (DHB)?
DHB is a hydrogenated derivative of berberine, offering higher bioavailability and enhanced metabolic benefits.
2. How is DHB different from berberine?
DHB is absorbed more efficiently in the body, requiring lower doses for equivalent efficacy compared to standard berberine.
3. Is this product naturally derived?
Yes, it is extracted from Golden Cypress (Berberis aristata) and purified to ≥98% using solvent-free methods.
4. Can DHB be used in dietary supplements?
Absolutely. It is widely formulated into capsules, tablets, and powders for metabolic and cardiovascular support.
5. What safety tests are performed?
Each batch undergoes heavy metal, pesticide residue, and microbial testing to meet FDA, EU, and China standards.
6. What is the recommended daily dosage?
Typical doses range from 50-300 mg/day, depending on application. Consult a healthcare provider for specific formulations.
7. Does DHB interact with medications?
DHB may interact with glucose-lowering drugs. Advise customers to consult a physician before use.
8. Can DHB be customized for bulk orders?
Yes, we offer custom particle sizes, solubility enhancements, and private-label packaging for OEM/ODM clients.