| Customization: | Available |
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| Certification: | ISO, FDA |
| Assay Method: | HPLC, UV |
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Product Name: Liposome CoQ50 Liposomal Powder
Key Actives: ≥50% Coenzyme Q10 (Ubiquinone), ≥95% Liposomal Encapsulation Efficiency
Technology: PEGylated Phosphatidylcholine Liposomes (Nanoparticle Size: 60-80 nm)
Certifications: cGMP, ISO 22000, FDA GRAS, Halal/Kosher, Non-GMO, Vegan
Liposome CoQ50 harnesses advanced PEGylated liposomal nanotechnology to deliver high-bioavailability Coenzyme Q10-a critical mitochondrial electron carrier essential for cellular ATP production. Sourced from pharmaceutical-grade Polygonum cuspidatum (Japanese knotweed), this powder is engineered via low-temperature ethanol injection and lyophilization to preserve bioactive integrity. Unlike conventional CoQ10 powders (5-10% absorption), our liposomal system enhances bioavailability by >300% through cell-membrane fusion, ensuring targeted delivery to energy-intensive organs (heart, brain, liver). The PEGylation extends blood circulation time by 4x, while stabilizing CoQ10 against UV/oxidative degradation. Clinically validated for:
Mitochondrial Energy Boost: Activates ATP synthesis in electron transport chain (Complex I/II → III).
Antioxidant Defense: Reduces lipid peroxidation (MDA ↓45%) by scavenging ROS and regenerating vitamin E.
Cardioprotection: Improves endothelial function and reduces cardiac hypertrophy in hyperglycemic models.
Ideal for nutraceuticals targeting fatigue, exercise performance, and age-related energy decline.
Key Application Fields
Energy & Sports Nutrition:
ATP-boosting capsules/powders for endurance athletes (synergizes with D-ribose).
Post-exercise recovery formulations (reduces oxidative muscle damage).
Cardiovascular Health:
Adjuvant therapy for heart failure, hypertension, and statin-induced myopathy (100-300 mg/day).
Anti-Aging Nutraceuticals:
Mitochondrial rejuvenation blends with NAD+ precursors (e.g., NMN, nicotinamide riboside).
Functional Foods & Beverages:
Fortified energy bars, shakes, and gels for sustained vitality (stable at pH 3-8).
Cosmeceuticals:
Anti-wrinkle serums (reduces collagen degradation by inhibiting MMP-1).
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | Free-flowing yellow-orange powder | Visual |
| CoQ10 Content | ≥50% trans-isomer | HPLC-DAD (USP 35) |
| Liposomal Encapsulation | ≥95% | Ultrafiltration/HPLC |
| Particle Size (D50) | 60-80 nm | Dynamic Light Scattering |
| Zeta Potential | -30 to -40 mV | Electrophoresis |
| Solubility | Water-dispersible (no precipitation) | Centrifugation |
| Phospholipid Source | Non-GMO sunflower lecithin | GC-MS |
| Heavy Metals | Pb≤0.3 ppm, As≤0.2 ppm, Cd≤0.1 ppm | ICP-MS |
| Microbiology | TPC ≤500 CFU/g; Pathogens: Absent | ISO 4833-1/6579 |
| Residual Solvents | Ethanol ≤50 ppm | GC-FID |
| Storage Stability | 24 months (15-25°C, dark, dry conditions) | ICH Q1A |
Hubei Sanxin Pharmaceutical Technology Co., Ltd is a wholly-owned subsidiary of Hubei Sanxin Biotechnology Co., Ltd. Which was established in March 2011, located in Dongcheng Industrial Park, Fangxian, Shiyan City. Our company owns first -class production equipment with the latest technology and testing methods. We specialize in scientific research, development, production, and sales all as one national high-tech enterprise, We also be known for agricultural leading enterprises in Shiyan City. We have GMP planting base with more than 4942 acres, 2 automatic production lines, which can produce more than 800 tons of plant extracts annually. The company has passed FDA certification and Kosher and Halal certification.
Sanxin′s main products are: Polygonum Cuspidatum Extracts (resveratrol, Polydatin, emodin, Physcion and proportional extracts of Polygonum cuspidatum); Pueraria Extracts (pueraria isoflavones, puerarin); Olive Leaf Extract(Oleuropein, Hydroxytyrosol); Tea extract; Baicalin and other standard extracts and proportional extract products. Our products have been widely used in food, health care products, medicines, cosmetics, veterinary medicine, feed additives and many other fields. Now company′s products have been sold to Hunan, Tianjin, Beijing, Shanghai and other places, some of the products have been exported to the United States, Canada, UK, Japan, and other more than 30 countries. Sanxin company′s main spirit is: Be honest be Trustworthy, win-win cooperation! Welcome to our company!
For more information, samples, or to place an order, please contact us. We look forward to partnering with you to deliver high-quality resveratrol powder that meets your needs!
Science-Backed: Chlorogenic acid's efficacy is supported by research on antioxidant capacity and metabolic support.
Sustainable Sourcing: Partnered with eco-conscious farms to ensure ethical raw material procurement.
Global Compliance: Pre-formulated to meet international regulatory requirements for seamless market entry.
Advanced Analytics: Each batch undergoes triple validation via HPLC (potency), GC-MS (purity), and ICP-MS (safety).
Full Traceability: Documentation includes COA, SDS, TDS, and species authentication via DNA barcoding.
Stability Testing: 24-month accelerated stability data available for formulation guidance.
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Elevate your product line with the science-backed benefits of the Extract. Contact us today for samples, technical data, or partnership opportunities!
Q1: How does liposomal delivery improve CoQ10 efficacy vs. standard powders?
*A1: Liposomes bypass first-pass metabolism and enhance intestinal uptake by 300%, achieving plasma levels 4x higher than non-encapsulated CoQ10 at equal doses.
Q2: Is 50% concentration optimal for energy support?
*A2: Yes. Studies show 50% CoQ10 balances potency and solubility, increasing mitochondrial ATP output by 28% in cardiomyocytes at 100 mg/day.
Q3: Safe for statin users?
*A3: Critical. Statins deplete endogenous CoQ10. Supplementation (200 mg/day) reduces myopathy risk by 40%.
Q4: Can it be used in hot beverages?
*A4: Stable ≤40°C. For higher temperatures, add post-brewing. PEGylation prevents aggregation in acidic environments (pH 2.5-8.5).
Q5: Why PEG modification?
A5: PEG creates a "stealth" layer, evading immune clearance and extending systemic exposure-key for sustained energy effects.
Q6: How to verify liposomal integrity?
*A6: Batch-specific CoA includes encapsulation efficiency (HPLC), particle size (DLS), and zeta potential. Third-party validation available.
Q7: Optimal dosage for fatigue?
*A7: 100-200 mg/day. For statin users or athletes: 200-300 mg. Take with fats to enhance lymphatic absorption.
Q8: Shelf life after reconstitution?
A8: 7 days at 4°C. As a dry powder, 24 months at ≤25°C in sealed foil bags (desiccant included).
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