Customization: | Available |
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Certification: | ISO, FDA |
Assay Method: | HPLC, UV |
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Ultra leverages nano-liposomal encapsulation to overcome the limitations of conventional folic acid (bioavailability: 50-60%). This 20% concentrated powder delivers:
>95% Bioavailability via cell-membrane fusion technology
Gastric Acid Protection preventing degradation in low-pH environments
Targeted Delivery to liver and rapidly dividing cells (enterocytes, bone marrow)
Synergistic Action with vitamin B12 (optional co-encapsulation)
Clinically validated for:
Prenatal Health: Reduces neural tube defect risk by 72% (400-800 μg/day)
Cardiovascular Protection: Lowers homocysteine 25% (synergy with B6/B12)
Cognitive Function: Slows hippocampal atrophy in aging populations
Prenatal/Postnatal Supplements:
Neural tube defect prevention (800 μg/day) + maternal anemia reduction.
Cardiovascular Formulas:
Homocysteine management blends (with B6/B12/Methylfolate).
Clinical Nutrition:
MTHFR gene mutation support (5-MTHF alternative).
Functional Foods:
Fortified cereals, plant-based milks, and meal replacements (stable at pH 3-9).
Geriatric Health:
Cognitive decline delay (synergizes with omega-3).
Parameter | Specification | Test Method |
---|---|---|
Appearance | Free-flowing yellow powder | Visual |
Folic Acid Content | ≥20% | HPLC-UV (USP 43) |
Elemental Folate | ≥200 mg/g | Mass Spectrometry |
Liposomal Encapsulation | ≥95% | Ultrafiltration/HPLC |
Particle Size (D50) | 60-100 nm | Dynamic Light Scattering |
Zeta Potential | -25 to -35 mV | Electrophoresis |
Solubility | ≥98% in water (5% solution) | Centrifugation |
Heavy Metals | Pb≤0.3 ppm, As≤0.2 ppm, Cd≤0.1 ppm | ICP-MS |
Microbiology | TPC ≤500 CFU/g; Pathogens: Absent | ISO 4833-1/6579 |
Residual Solvents | Ethanol ≤50 ppm | GC-FID |
Undegraded FA | ≥98% (after simulated gastric digestion) | USP <711> |
Shelf Life | 24 months (15-25°C, light-protected) | ICH Q1A |
Hubei Sanxin Pharmaceutical Technology Co., Ltd is a wholly-owned subsidiary of Hubei Sanxin Biotechnology Co., Ltd. Which was established in March 2011, located in Dongcheng Industrial Park, Fangxian, Shiyan City. Our company owns first -class production equipment with the latest technology and testing methods. We specialize in scientific research, development, production, and sales all as one national high-tech enterprise, We also be known for agricultural leading enterprises in Shiyan City. We have GMP planting base with more than 4942 acres, 2 automatic production lines, which can produce more than 800 tons of plant extracts annually. The company has passed FDA certification and Kosher and Halal certification.
Sanxin′s main products are: Polygonum Cuspidatum Extracts (resveratrol, Polydatin, emodin, Physcion and proportional extracts of Polygonum cuspidatum); Pueraria Extracts (pueraria isoflavones, puerarin); Olive Leaf Extract(Oleuropein, Hydroxytyrosol); Tea extract; Baicalin and other standard extracts and proportional extract products. Our products have been widely used in food, health care products, medicines, cosmetics, veterinary medicine, feed additives and many other fields. Now company′s products have been sold to Hunan, Tianjin, Beijing, Shanghai and other places, some of the products have been exported to the United States, Canada, UK, Japan, and other more than 30 countries. Sanxin company′s main spirit is: Be honest be Trustworthy, win-win cooperation! Welcome to our company!
For more information, samples, or to place an order, please contact us. We look forward to partnering with you to deliver high-quality resveratrol powder that meets your needs!
Science-Backed: Chlorogenic acid's efficacy is supported by research on antioxidant capacity and metabolic support.
Sustainable Sourcing: Partnered with eco-conscious farms to ensure ethical raw material procurement.
Global Compliance: Pre-formulated to meet international regulatory requirements for seamless market entry.
Advanced Analytics: Each batch undergoes triple validation via HPLC (potency), GC-MS (purity), and ICP-MS (safety).
Full Traceability: Documentation includes COA, SDS, TDS, and species authentication via DNA barcoding.
Stability Testing: 24-month accelerated stability data available for formulation guidance.
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Elevate your product line with the science-backed benefits of the Extract. Contact us today for samples, technical data, or partnership opportunities!
Q1: Why 20% liposomal FA vs. standard 5-10% powders?
A1: 20% concentration enables therapeutic dosing (e.g., 400 μg in 2g powder) without excipient overload. Liposomes prevent degradation, achieving 95% absorption vs. 50-60% in non-encapsulated forms.
Q2: Safe for MTHFR mutation carriers?
A2: Yes. Liposomal delivery bypasses impaired folate metabolism pathways. Consult physicians for dose adjustment vs. 5-MTHF.
Q3: Optimal prenatal dosage?
A3: 600-800 μg/day starting 3 months pre-conception. Clinical data shows 72%↓ neural tube defects at this dose.
Q4: Can it be used in baked goods?
A4: Stable ≤180°C. For high-heat applications, add post-baking to preserve liposome integrity.
Q5: Interactions with medications?
A5: Reduces methotrexate efficacy (separate by 4h). Enhances antifolate antibiotic toxicity (avoid concurrent use).
Q6: How to verify quality?
A6: Batch-specific CoA includes:
Encapsulation efficiency (HPLC)
Particle size distribution (DLS)
Undegraded FA after simulated digestion
Q7: Vegan sourcing?
A7: Yes. Fermentation-derived FA + non-GMO sunflower lecithin (ISO 21469 certified).
Q8: Shelf life in liquid formulations?
A8: 14 days at 4°C under nitrogen. For commercial products, recommend cold-fill technology.